Click on one of your cards to play it. If you can't play, press draw. So that you can't see your opponent's cards at the same time as yours, a black rectangle will hide their cards when it's your turn. A slight difference in the +4 and change color cards, the color automatically changes to that of the card. A green +4 changes the color to green, while a red change color changes it to... you guessed it, red.
An AI version is expected to come out sometime next week. Request games in the comments